Dr. Benjamin H. Krasne, M.D.
Board-certified physicianBoard-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.
Weekly semaglutide, compounded for you
Compounded semaglutide online for weight loss
Compounded semaglutide is made for an individual patient by a licensed U.S. compounding pharmacy. It is not FDA-approved, so it pays to understand what that means before you start.
- Free 5–10 minute consultation
- $149/mo with clinician follow-up
- Clear dosing in units and milligrams
Free to book. You pay only if you go ahead with treatment.
$149per month
Licensed U.S. clinician review
Made by: Licensed U.S. compounding pharmacy
$149/motransparent price
5–10 minphone or video
No insuranceneeded
LicensedU.S. clinicians
Why get compounded semaglutide through My IV Doctors
Honest brand comparison
Your clinician walks you through brand and compounded options side by side, including FDA status and cost, so you can choose with the full picture.
Filled by licensed U.S. pharmacies
If treatment is appropriate, your prescription goes to a licensed U.S. compounding pharmacy. Compounded semaglutide is not FDA-approved, and we tell you so up front.
Dosing you can follow
You get plain-language instructions in both units and milligrams, plus habits that help prevent the measuring mistakes the FDA has warned about.
Support at every step
Follow-up visits cover dose changes, side effects and refills, and your care team keeps track of changing compounding rules so you don't have to.
How to get compounded semaglutide online
- 1
Pick a time for your free visit
Pick phone or video and share your history, current medicines and goals in a short intake.
- 2
Talk with a clinician
In 5–10 minutes a licensed U.S. clinician compares brand and compounded semaglutide with you and decides what is appropriate.
- 3
Get your prescription filled
If prescribed, a licensed U.S. compounding pharmacy prepares it for you and labels the dose in both milligrams and syringe units.
- 4
Measure each dose and check in
Check the label against your instructions before every dose. Report side effects at each check-in as your dose rises.
Who compounded semaglutide is for
BMI of 30 or higher (or 27 with a condition)
Generally a BMI of 30 or more, or 27 or more with a condition such as high blood pressure, prediabetes or sleep apnea.
A documented clinical reason
Federal rules limit copies of commercially available drugs, so your clinician records why a compounded preparation suits you, such as a dose adjustment.
Comfortable with vials and syringes
You need to draw up a measured amount each week and follow the label exactly.
Thyroid cancer history or pregnancy
Skip it with medullary thyroid cancer (yours or a family member's) or MEN 2, during pregnancy, or if you prefer an FDA-approved product.
Compounded semaglutide vs. brand Wegovy
| Feature | Compounded semaglutide | Wegovy (brand semaglutide) |
|---|---|---|
| FDA status | Not FDA-approved | FDA-approved |
| Made by | Licensed U.S. compounding pharmacy | Novo Nordisk |
| Form | Vial with syringe | Prefilled pen or daily tablet |
| Measuring a dose | Draw to the unit mark on your label | Preset doses |
| Price | $149/mo | From $199/mo; brand medication may cost extra |
Compounded semaglutide, explained
Compounding is when a licensed pharmacist prepares a medication for a specific patient from a prescription, rather than dispensing a factory-made product. Compounded semaglutide is usually supplied as a liquid in a vial that you draw into a syringe and inject once a week.
Because it is compounded, the FDA does not review it for safety, effectiveness or quality before it reaches you. Brand products such as Wegovy and Ozempic went through that review; compounded versions did not. That does not make every compounded product unsafe, but it does mean the pharmacy you use, and how carefully you measure each dose, matter a great deal.
Your clinician will tell you plainly whether a compounded option is available and appropriate for you, how it compares with FDA-approved semaglutide, and what to do if your situation changes.
Compounded semaglutide FDA rules in 2026
During the national shortage of semaglutide injections, pharmacies had more room to compound it. The FDA determined that shortage was resolved on February 21, 2025, and the grace periods for compounders have since ended.
Today, state-licensed 503A pharmacies may still compound for an individual patient based on a prescription, but making what the FDA calls essentially copies of a commercially available drug is restricted. A prescriber can document a significant clinical difference for a specific patient. Larger 503B outsourcing facilities face tighter limits, and in April 2026 the FDA proposed excluding semaglutide from the list of bulk substances they may use. That proposal had not been finalized when this page was reviewed.
These rules can change. Your clinician and pharmacy keep track of them so you do not have to.
How to measure a compounded semaglutide dose
The FDA has received reports of people hospitalized after dosing errors with compounded semaglutide, often from confusing milligrams, milliliters and syringe units. A few habits prevent most of these mistakes.
- Read the concentration on every new vial, because it can differ between refills.
- Use the syringe type your pharmacy specifies and draw to the exact unit mark on your label.
- Never raise your dose faster than your plan, even if you feel fine.
- Ask your pharmacist or clinician to confirm the numbers whenever anything looks different.
Compounded semaglutide side effects and safety
Compounded semaglutide shares the known risks of the semaglutide molecule, plus risks that come from compounding itself, such as dosing errors and variation between pharmacies.
- Stomach effects such as nausea, vomiting, diarrhea and constipation are the most common, especially after a dose increase.
- Not for anyone with medullary thyroid cancer (yours or a family member's) or MEN 2; report a neck lump, hoarseness or trouble swallowing.
- Severe, persistent belly pain can point to pancreatitis or gallbladder problems and needs urgent care.
- The FDA warns that semaglutide sodium and semaglutide acetate are different from the ingredient in approved products; ask what your pharmacy uses.
- Stop at least 2 months before trying to conceive, and do not use during pregnancy.
Physicians who oversee your care
Independently licensed U.S. physicians supervise every treatment we offer.
Dr. Johnathan Chance Miller, M.D.
PhysicianTrained at Columbia and Washington University, he pairs prescriptions with practical habits around food, training and sleep.
Dr. Vanessa Niles, R.N., M.D., F.A.C.O.G.
OB-GYN, board certifiedAn OB-GYN for more than 40 years and a Fellow of ACOG, she leads women's health care, from perimenopause to PCOS.
Compounded semaglutide FAQs
Still deciding? The first consultation is free and takes about 5–10 minutes.
Book a free consultationDoes compounded semaglutide have FDA approval?
No. Compounded drugs are not FDA-approved, and the FDA does not check them for safety, effectiveness or quality before they are dispensed. Brand products such as Wegovy and Ozempic are FDA-approved.
Is compounded semaglutide still legal after the shortage ended?
State-licensed pharmacies may compound for individual patients with a prescription. Copies of commercially available drugs are restricted, but a prescriber can document a significant clinical difference for a particular patient. Your clinician explains whether that applies to you.
What is the difference between a 503A and 503B pharmacy?
A 503A pharmacy is a state-licensed pharmacy that compounds for specific patients based on prescriptions. A 503B outsourcing facility registers with the FDA and can make larger batches, but it faces strict limits on which bulk ingredients it may use. In April 2026, the FDA proposed keeping semaglutide off the bulk substances list for 503B facilities; a final decision was still pending when this page was reviewed.
What are semaglutide sodium and semaglutide acetate?
They are salt forms that some compounders have used. The FDA says they are different active ingredients from the one in approved products and that it knows of no lawful basis for compounding with them. It is reasonable to ask your pharmacy which form it uses.
How many units of compounded semaglutide should I take?
Compounded semaglutide comes as a liquid, and insulin-style syringes are marked in units rather than milligrams. How many units equal your dose depends on the vial's concentration. Always follow the unit number on your current label.
Is semaglutide with B12 better?
Some pharmacies add B12 to compounded semaglutide. There is no FDA-approved semaglutide product with B12, and the FDA has said adding another ingredient does not automatically make a product something other than a copy. Your clinician can tell you whether it adds anything for you.
How do I store compounded semaglutide?
Follow the storage directions on your pharmacy label, which usually call for refrigeration. Do not freeze it, keep it away from light, and throw it out by the beyond-use date printed on the label.
Is compounded semaglutide the same strength as Wegovy?
Doses are expressed in milligrams just like Wegovy, but the liquid concentration and the way you measure it differ. Your clinician sets a schedule that climbs gradually, similar in shape to brand dosing.
Can I switch from compounded semaglutide to Wegovy?
Yes, if your clinician agrees it is appropriate. Because the ingredient is the same, they can usually choose a sensible starting point on the brand product. Brand medication may cost more.
Can I buy compounded semaglutide without a prescription?
Legitimate compounded semaglutide always requires a prescription. Websites selling it without one, or selling products labeled for research use, are not a safe source. The FDA has warned about unapproved GLP-1 products sold this way.
How much does compounded semaglutide cost?
The program price is $149/mo. Your clinician confirms exactly what is included and the total cost before anything is prescribed, so there are no surprises.
What should I do if I take too much semaglutide?
Call your clinician or Poison Control at 1-800-222-1222 right away. Severe nausea, vomiting, dizziness or signs of low blood sugar after a possible overdose need prompt medical care.
Start compounded semaglutide with a free consultation
Book a free 5–10 minute phone or video visit. A licensed clinician will review brand and compounded options with you, and plans are $149/mo if treatment is appropriate.
Related treatments
References
- FDA's concerns with unapproved GLP-1 drugs used for weight loss – FDA
- FDA clarifies policies for compounders as national GLP-1 supply begins to stabilize – FDA
- FDA proposes to exclude semaglutide, tirzepatide and liraglutide from the 503B bulks list – FDA
- Semaglutide injection – MedlinePlus
Medically reviewed October 2026. This page is general information and not a substitute for advice from your own clinician. Read our editorial policy.
$149per month
Book a free consultation