
Dr. Benjamin H. Krasne, M.D.
Board-certified physicianBoard-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.
Weight loss
GLP-1 shots, daily pills and non-GLP-1 options, prescribed after a free visit.
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Brand-name injections
Pills and other options
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Compare GLP-1 options, prescribed online
Weekly shots, daily shots and daily pills all fall under the GLP-1 umbrella. This guide compares them, and a free 5–10 minute visit with a licensed clinician helps you choose.
Free to book. You pay only if you go ahead with treatment.
Semaglutide, tirzepatide, liraglutide and GLP-1 pills are all considered, so your clinician can match the medicine to your health and routine.
If a GLP-1 is prescribed, you get a step-by-step dose-increase plan for that specific medicine, plus guidance on handling early side effects.
Follow-up visits let you review progress and side effects. If a medicine isn't working for you, your clinician can discuss switching to another option.
Prescriptions go only to licensed U.S. pharmacies. If a compounded medicine is prescribed, you're told plainly that it is not FDA-approved.
You do not need to know which medicine you want. Pick a phone or video slot online.
In 5–10 minutes a licensed U.S. clinician reviews your weight, conditions, medicines, past GLP-1 use and preferences about shots or pills.
If a GLP-1 is appropriate, your clinician recommends a specific medicine and form, explains the cost and prescribes it.
Almost every GLP-1 starts low and increases over weeks. Follow-ups adjust the pace and check that the medicine is still the best fit.
Weight-management GLP-1s are approved for adults with a BMI of 30 or more.
A BMI of 27 or more with a condition such as high blood pressure, type 2 diabetes, high cholesterol or sleep apnea.
Several GLP-1 brands, including Ozempic, Mounjaro and Rybelsus, are approved specifically to lower blood sugar.
Zepbound is approved for moderate to severe obstructive sleep apnea in adults with obesity.
A personal or family history of medullary thyroid carcinoma or MEN 2, pregnancy, severe gastroparesis or a history of pancreatitis that needs specialist review. Your clinician screens for each.
| Medicine | Form | How often | FDA status |
|---|---|---|---|
| Semaglutide (Wegovy, Ozempic) | Injection | Weekly | FDA-approved |
| Semaglutide pills (Wegovy pill, Rybelsus) | Tablet | Daily | FDA-approved |
| Tirzepatide (Zepbound, Mounjaro) | Injection | Weekly | FDA-approved |
| Liraglutide (Saxenda, Victoza, generics) | Injection | Daily | FDA-approved |
| Orforglipron (Foundayo) | Tablet | Daily | FDA-approved |
| Compounded semaglutide or tirzepatide | Varies | Varies | Not FDA-approved |
GLP-1 receptor agonists copy a hormone your gut releases when you eat. They tell your brain you are full, slow the emptying of your stomach and help the pancreas release insulin only when blood sugar is high. For weight management, the main effect most people notice is that hunger and food thoughts become quieter.
Several medicines share this action but differ in how often you take them, how strong their effect is and which conditions they are approved for. Semaglutide and liraglutide act on the GLP-1 receptor alone. Tirzepatide also acts on the GIP receptor. Some are weekly injections, one is a daily injection, and there are now daily pills approved for weight management.
There is no single best GLP-1 for everyone. The right choice depends on your health conditions, how you feel about injections, side effects you have had before and cost. A licensed U.S. clinician at My IV Doctors can go through the options with you and prescribe one when it is appropriate.
Here is a quick map of the options you may hear about. Brand names belong to their manufacturers, and brand medication may cost more than the starting plan price.
Strength of effect: in their own trials, tirzepatide has generally produced the largest average weight loss, followed by semaglutide, with liraglutide and the pills tending to produce less. Individual responses overlap a lot.
Routine: weekly injections mean one dose a week. Daily pills avoid needles but need to be taken every day, and some have rules about food and water. Daily liraglutide suits people who like a daily habit.
Health conditions: sleep apnea, type 2 diabetes and heart disease each point toward particular medicines with matching approvals. Your clinician will match the medicine to your conditions.
The FDA has warned that compounded GLP-1 drugs are not reviewed by the agency for safety, effectiveness or quality, and that some people have been hospitalized after measuring doses incorrectly. It has also warned about products sold online as research chemicals or not for human use. We only prescribe through licensed U.S. pharmacies, and if a compounded medicine is prescribed, your clinician tells you plainly that it is not FDA-approved.
These medicines share a similar safety profile. The details differ slightly by product, and your clinician reviews the label for the one you are prescribed.
Independently licensed U.S. physicians supervise every treatment we offer.

Board-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.

Trained at Columbia and Washington University, he pairs prescriptions with practical habits around food, training and sleep.

An OB-GYN for more than 40 years and a Fellow of ACOG, she leads women's health care, from perimenopause to PCOS.
Still deciding? The first consultation is free and takes about 5–10 minutes.
Book a free consultationIt is a prescription for a medicine that acts on the GLP-1 hormone receptor, such as semaglutide, tirzepatide or liraglutide. These are used for weight management, type 2 diabetes or both, depending on the brand.
Plans start from $149/mo, and the first consultation is free. The exact price depends on the medicine and dose, and brand medication may cost more; your clinician confirms the total before prescribing.
In their own trials, tirzepatide has generally led to the largest average weight loss, followed by semaglutide. But the best medicine for you also depends on side effects, conditions and cost.
Yes. The Wegovy pill (oral semaglutide) and Foundayo (orforglipron) are daily pills approved for weight management. Rybelsus is an oral semaglutide approved for type 2 diabetes.
Both contain semaglutide. Wegovy is approved for weight management and Ozempic for type 2 diabetes, with different dose ranges.
No. Compounded versions are made by compounding pharmacies and are not FDA-approved, so the FDA has not reviewed their safety, effectiveness or quality. Brand and generic products are FDA-approved.
Yes, with your clinician's guidance. They will choose a safe starting dose for the new medicine based on what you have been taking.
Usually you need a BMI of 30 or more, or 27 or more with a weight-related condition, or a diagnosis of type 2 diabetes for the diabetes brands. Your clinician also checks for reasons it would be unsafe.
They are designed for long-term use. Many people regain weight after stopping, so plan your long-term approach with your clinician.
Digestive symptoms such as nausea and constipation are the most common and usually ease over a few weeks. Raising the dose slowly helps.
Tirzepatide can make oral contraceptives less reliable after starting and after dose increases. Ask your clinician about backup contraception for the medicine you are prescribed.
There are other options, such as bupropion-naltrexone tablets, depending on your history. Your clinician can talk through alternatives.
No. You can book and be treated without insurance. Some people use insurance for brand medicines separately; ask your clinician if that applies to you.
Plans start from $149 a month, and booking is free with no insurance needed. Talk with a licensed clinician for 5–10 minutes by phone or video to find your fit.
Medically reviewed October 2026. This page is general information and not a substitute for advice from your own clinician. Read our editorial policy.