
Dr. Benjamin H. Krasne, M.D.
Board-certified physicianBoard-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.
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For hot flashes, night sweats, poor sleep and vaginal dryness around menopause, a licensed clinician can walk you through hormone therapy and its risks in a short phone or video visit. Plans start from $149 a month.
Free to book. You pay only if you go ahead with treatment.
Hormone therapy may ease hot flashes, night sweats, poor sleep and vaginal dryness, and those symptoms often start easing within a few weeks.
Your clinician helps you choose a patch, gel, pill or vaginal estrogen, plus progesterone if you have a uterus, based on your health and preferences.
A licensed clinician looks at your symptoms, medical history and family history before prescribing, and revisits the balance of benefits and risks at every check-in.
Plans from $149/mo cover follow-up for dose changes, lab orders when recommended and a yearly review, with non-hormonal options if hormones aren't right.
Choose a phone or video appointment. The first consultation is free, and you do not need insurance.
In about 5–10 minutes, a licensed clinician asks about your periods, symptoms and medicines, plus any personal or family history of cancer and clots. Labs or a recent mammogram may be requested.
If HRT is appropriate, you receive a prescription for the form and dose that suits you, with instructions on what to expect in the first weeks.
Check in after the first couple of months and then regularly. Your clinician can change the dose or form, and reviews whether to continue at least once a year.
Systemic estrogen is one of the most effective treatments for these symptoms, which can disrupt work and sleep for years.
Night sweats and hormonal shifts can break up sleep and affect mood. Treating the underlying symptoms often helps.
Low-dose vaginal estrogen can restore comfort and is an option even for many women who do not want systemic hormones.
Women who reach menopause before 45, or before 40, are often advised to consider hormone therapy at least until the usual age of menopause, partly to protect bone.
A history of breast or uterine cancer, blood clots, stroke, heart attack, active liver disease or unexplained vaginal bleeding usually rules out systemic HRT online and needs in-person specialist care.
| Form | How it's absorbed | Often suits | Notes |
|---|---|---|---|
| Skin patch, gel or spray | Through the skin, bypassing the liver | Migraine, higher triglycerides or higher clot risk | Relieves whole-body symptoms |
| Pill | Passes through the liver first | Those who want a simple daily tablet | Slightly higher clot risk than skin forms |
| Vaginal cream, tablet or ring | Mostly local, little reaches the bloodstream | Dryness, irritation and urinary symptoms | Low dose |
| Progesterone | Taken daily or in cycles | Anyone with a uterus taking estrogen | Protects the uterine lining |
Menopause is confirmed after 12 months in a row without a period, and for most women it happens somewhere between 45 and 55. As the ovaries make less estrogen, many women get hot flashes, night sweats, disturbed sleep, mood changes, vaginal dryness and discomfort with sex. Lower estrogen also speeds up bone loss. Hormone replacement therapy, now often called menopausal hormone therapy, replaces some of that estrogen to ease symptoms.
The core of most plans is estradiol, given as a skin patch, gel, spray or pill. If you still have a uterus, you also need a progestogen such as micronized progesterone, because estrogen alone can thicken the uterine lining and raise the risk of endometrial cancer. Women whose main problem is vaginal dryness or urinary symptoms may only need low-dose vaginal estrogen, which acts mostly where it is applied.
Thinking about the risks has shifted. In November 2025, the FDA began removing the broad boxed warnings about heart disease, breast cancer and probable dementia from menopausal hormone therapy labels, while keeping a boxed warning about endometrial cancer for systemic estrogen-alone products. The FDA noted that starting therapy within 10 years of menopause or before age 60 may carry a more favorable balance of benefits and risks. Your clinician will still weigh your personal and family history before recommending anything.
Every form can relieve symptoms. The choice depends on your health, preferences and how your body responds.
Hot flashes and night sweats often start easing within a few weeks, with fuller effect over two to three months. Breast tenderness, bloating and spotting are common early on and often settle. Irregular bleeding that continues beyond the first months, or any bleeding after it has stopped, should be reported so your clinician can arrange an evaluation.
There is no fixed time limit for HRT. Many women take it for several years; some take it longer. The decision is revisited regularly based on your symptoms, age and health. When you stop, a gradual reduction can make returning symptoms easier to manage.
Non-hormonal prescription options for hot flashes include certain antidepressants such as low-dose paroxetine, gabapentin and newer medicines like fezolinetant that act on the brain's temperature control center. Lubricants and moisturizers can help vaginal dryness. Your clinician can talk through these if hormones are not right for you.
HRT has real benefits and real risks, and the balance is personal. Your clinician will review your history before prescribing and at every check-in.
Independently licensed U.S. physicians supervise every treatment we offer.

Board-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.

Trained at Columbia and Washington University, he pairs prescriptions with practical habits around food, training and sleep.

An OB-GYN for more than 40 years and a Fellow of ACOG, she leads women's health care, from perimenopause to PCOS.
Still deciding? The first consultation is free and takes about 5–10 minutes.
Book a free consultationPlans start from $149 a month. The first consultation is free, and you do not need insurance. Brand-name products may cost extra.
For many healthy women who start within about 10 years of menopause or before 60, the benefits often outweigh the risks. It is not right for women with certain cancers, clotting disorders or liver disease. Your clinician will look at your history to help you decide.
In November 2025, the FDA began removing the boxed warnings about heart disease, breast cancer and probable dementia from menopausal hormone therapy labels. A boxed warning about endometrial cancer remains for systemic estrogen-alone products. Product labels are being updated over time.
If you have a uterus and take systemic estrogen, yes. Progesterone protects the uterine lining from overgrowth. If you have had a hysterectomy, you usually do not need it.
Menopause is usually diagnosed from your age and symptoms, so hormone levels are not always needed. Your clinician may still order labs or ask about recent screening based on your health.
Many women notice fewer hot flashes within a few weeks, with fuller relief by about three months. Vaginal symptoms can take a little longer to improve.
Estradiol and micronized progesterone are chemically identical to the hormones the body makes and are available as FDA-approved products. Custom compounded hormone mixes are not FDA-approved and are not proven safer or more effective.
Studies have not shown that HRT itself causes weight gain. Weight often shifts toward the middle around menopause regardless of treatment, and exercise and diet still matter.
There is no set cutoff. Your clinician reviews your symptoms and risks at least yearly, and you decide together whether to continue, lower the dose or taper off.
Yes. If dryness, irritation, pain with sex or urinary symptoms are your main concern, low-dose vaginal estrogen may be all you need, and it has very little effect on the rest of the body.
Often, yes. Your clinician may ask for labs, a blood pressure reading or up-to-date breast and cervical screening, and will refer you for in-person care if anything needs an exam.
Testosterone is not FDA-approved for women in the U.S. Some clinicians consider low doses off-label for low desire after menopause. Ask your clinician whether it is relevant for you.
Non-hormonal medicines such as low-dose paroxetine, gabapentin and fezolinetant can reduce hot flashes. Lubricants, moisturizers and lifestyle changes can help other symptoms.
Book a free 5–10 minute phone or video consultation. A licensed clinician will review your symptoms and risks, and plans start from $149/mo if HRT is appropriate.
Medically reviewed October 2026. This page is general information and not a substitute for advice from your own clinician. Read our editorial policy.