
Dr. Benjamin H. Krasne, M.D.
Board-certified physicianBoard-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.
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4-in-1 hair loss topical, prescribed online
Our compounded 4-in-1 topical combines minoxidil, finasteride, ketoconazole and latanoprost in a single scalp application. A licensed clinician checks that it suits your type of hair loss and health first.
Free to book. You pay only if you go ahead with treatment.
Minoxidil, finasteride, ketoconazole and latanoprost are combined in a single scalp topical, so you apply one product instead of juggling several.
A licensed clinician reviews your hair loss pattern and health before prescribing, and flags sudden or patchy loss that needs a different approach.
Your formula is compounded by a licensed U.S. pharmacy. Like all compounded medicines, it is not FDA-approved, and your clinician explains what that means.
Your care team checks your progress and side effects over the months it takes to judge results, and answers questions as they come up.
Choose phone or video. In about 5–10 minutes, a licensed clinician asks about your hair loss pattern, family history, past treatments and general health.
Clear photos of your hairline and crown help your clinician confirm the pattern and give you a baseline for later comparison.
If your clinician decides treatment is appropriate, a licensed U.S. compounding pharmacy prepares the 4-in-1 topical and ships it with directions.
Use it as directed every day, and take photos in the same light at regular intervals. Your clinician reviews progress and side effects at follow-up.
Thinning at the crown or temples that has developed gradually is the classic pattern this formula targets.
Combining ingredients means one routine instead of juggling separate bottles, which can make it easier to stay consistent.
Treatment tends to work best at keeping the hair you have. Starting while thinning is mild generally gives you more to preserve.
Finasteride can harm a male fetus. Women who are pregnant or could become pregnant should not use this formula or touch treated skin. Your clinician can discuss other options for women.
Rapid shedding, round bald patches or scalp pain can point to other causes, such as thyroid problems, iron deficiency or alopecia areata, that need a different workup.
| Option | 4-in-1 topical | Topical minoxidil | Oral finasteride |
|---|---|---|---|
| Form | Compounded scalp topical | Solution or foam | Tablet |
| Active ingredients | Minoxidil, finasteride, ketoconazole and latanoprost | Minoxidil | Finasteride |
| FDA status | Compounded, not FDA-approved | FDA-approved for hair loss | FDA-approved for male pattern hair loss |
| Time to judge results | 4+ months | At least 4 months | At least 3 months |
The most common kind of hair loss is pattern hair loss, also called androgenetic alopecia. In men it usually shows as a receding hairline or thinning crown, and in women as a widening part or overall thinning. It is driven by genetics and by a hormone called DHT, which gradually shrinks sensitive hair follicles so they produce thinner, shorter hairs.
Two medicines have the strongest track record. Finasteride lowers DHT, and minoxidil keeps follicles in their growth phase longer. Both are FDA-approved for hair loss in their standard forms, finasteride as an oral tablet for men and minoxidil as a topical solution or foam.
Our 4-in-1 formula puts finasteride and minoxidil together in a topical with two supporting ingredients, ketoconazole and latanoprost. It is prepared by a licensed U.S. compounding pharmacy and, like all compounded medicines, is not FDA-approved. No topical finasteride product is FDA-approved, and the FDA has asked prescribers to explain its possible side effects clearly.
Each ingredient has a different job. The two main actives have the strongest evidence. The other two are added for supporting effects, with less research behind their use for hair.
Hair grows slowly, so patience matters. MedlinePlus advises that topical minoxidil takes at least 4 months, and possibly up to a year, before effects appear, and that finasteride usually needs at least 3 months. Some people notice extra shedding in the first weeks, which often settles as follicles reset.
The benefits last only as long as you keep using treatment. When minoxidil is stopped, most new hair is typically lost within a few months, and hair regained with finasteride is generally lost within a year of stopping. Think of this as ongoing care rather than a short course.
Applying finasteride to the scalp lowers but does not remove the chance of side effects. In 2025, the FDA reported adverse events with compounded topical finasteride, including erectile dysfunction, lower libido, anxiety, depression and suicidal thoughts, and most reports said symptoms continued after stopping.
Independently licensed U.S. physicians supervise every treatment we offer.

Board-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.

Trained at Columbia and Washington University, he pairs prescriptions with practical habits around food, training and sleep.

An OB-GYN for more than 40 years and a Fellow of ACOG, she leads women's health care, from perimenopause to PCOS.
Still deciding? The first consultation is free and takes about 5–10 minutes.
Book a free consultationMinoxidil, finasteride, ketoconazole and latanoprost, combined in one topical. It is compounded by a licensed U.S. pharmacy and is not FDA-approved.
The 4-in-1 formula is $199. Your first consultation is free and you do not need insurance. Your clinician confirms the cost and supply before you commit.
Most people need at least 4 months of daily use, and sometimes up to a year, to judge results. Photos taken in the same light every few months make changes easier to see.
Applying it to the scalp is intended to reduce exposure to the rest of the body, but side effects can still happen. The FDA has received reports of sexual and mood side effects with compounded topical finasteride, some lasting after people stopped.
Not if they're pregnant or could become pregnant, because finasteride can harm a male fetus. Your clinician can discuss other options suited to female pattern hair loss.
Hair loss usually resumes. Most new hair from minoxidil is lost within a few months, and gains from finasteride generally fade within a year.
Some people notice extra shedding in the early weeks as follicles move into a new growth cycle. It often settles, but tell your clinician if it worries you.
Ketoconazole is an antifungal that helps with dandruff and scalp inflammation, and latanoprost is a glaucoma drug that lengthens eyelashes. Both are added for supporting effects, with less evidence for hair than minoxidil or finasteride.
Let the product dry fully and wash your hands after applying. Women who are or could become pregnant should avoid touching treated skin, and children should not come into contact with it.
It can help slow loss, but crown thinning often responds better than the hairline. Your clinician can set realistic expectations based on your pattern.
Usually not for typical pattern hair loss. If your loss is sudden, patchy or comes with other symptoms, your clinician may order labs to look for thyroid or iron problems.
Testosterone therapy can speed up pattern hair loss in some men. Your clinician will consider your full treatment plan before prescribing.
Your clinician can review whether the diagnosis is right and discuss other approaches. Some people do better with different strengths or other evidence-based treatments.
Talk with a licensed clinician by phone or video in 5–10 minutes. If the 4-in-1 topical suits your hair loss, it's $199 and made by a licensed U.S. pharmacy.
Medically reviewed October 2026. This page is general information and not a substitute for advice from your own clinician. Read our editorial policy.