
Dr. Benjamin H. Krasne, M.D.
Board-certified physicianBoard-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.
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MIC + B12 shots, prescribed online
Lipotropic shots combine methionine, inositol and choline with vitamin B12. They can play a supporting role in a weight loss plan, and a licensed clinician can prescribe them for home use from $69 a month.
Free to book. You pay only if you go ahead with treatment.
Your clinician explains what MIC + B12 shots can and can't do, and how they may support a diet or weight loss medication plan.
A licensed clinician checks your history and medications before prescribing, since compounded blends are not FDA-approved.
Your monthly supply ships from a licensed U.S. pharmacy, with clear home injection steps and sharps disposal instructions.
Message the care team with questions, and review your progress with your clinician after the first four to six weeks.
Pick a time online. Booking is free, and you don't need insurance.
A licensed clinician talks with you for about 5–10 minutes by phone or video about your weight loss plan, diet, medicines and medical history. Labs may be requested if needed.
If lipotropic injections are appropriate, your clinician sends the prescription to a licensed U.S. compounding pharmacy, and the medication ships to you.
You get clear instructions on dosing, injection sites and sharps disposal. Most people begin with one shot a week.
After several weeks, your clinician checks how you're doing and whether to continue, change the frequency or stop.
Lipotropic shots are meant as an add-on to nutrition changes, exercise or medication, not a replacement for them.
When you cut calories, it can be harder to get enough of some nutrients. A clinician may suggest B12 and choline support as part of the bigger picture.
According to the NIH, most people in the U.S. get less choline than recommended. Eggs, meat, fish, dairy and some vegetables are the main food sources.
Vegans and vegetarians can run low on B12, and sometimes on choline, since both are concentrated in animal foods.
People who are pregnant or breastfeeding, have a cobalt or B12 allergy, or have serious liver or kidney disease should discuss alternatives with a clinician. These shots aren't for anyone looking for a stand-alone weight loss fix.
| Feature | Lipotropic (MIC + B12) | B12 shot | Fat-dissolving injection |
|---|---|---|---|
| Contains | Methionine, inositol, choline and B12 | Vitamin B12 only | — |
| Main use | Support during a weight loss plan | B12 support | Cosmetic, local fat |
| Targets one area | No | No | Yes, such as under the chin |
| Weight loss drug | No | No | No |
| Price here | From $69/mo | — | — |
"Lipotropic" describes nutrients involved in how the liver handles fat. The classic lipotropic injection, often called an MIC shot, blends three of them: methionine, an essential amino acid; inositol, a vitamin-like compound found in fruits, beans and grains; and choline, a nutrient your liver uses to move fat out of liver cells. Most blends also include vitamin B12, and some add other B vitamins.
These shots are not a fat burner. There's little good evidence that lipotropic injections cause meaningful weight loss on their own, and you should be wary of anyone who markets them that way. Where they may fit is alongside a real plan, such as a calorie-controlled diet, more activity or a prescription weight loss medication, for people who want extra nutrient support while they work on that plan.
Lipotropic blends are prepared by licensed U.S. compounding pharmacies and are not FDA-approved. The FDA does not check compounded products for safety, effectiveness or quality before they're sold, which is one reason a clinician reviews your health before prescribing.
Each component has a known role in the body. What's less certain is how much injecting them adds for someone who already eats a reasonably varied diet. Your clinician will be honest about that.
A common plan is a 1 mL injection once or twice a week, given into a muscle such as the upper arm or thigh, or under the skin of the belly, as your clinician prescribes. Most people start weekly and review after four to six weeks.
Some people say they feel more energetic, but experiences vary and the research is limited. Any weight change will come mainly from your eating pattern, activity and any weight loss medication you take. Pricing starts at $69 a month and depends on the blend and how often you inject; your clinician confirms the cost before prescribing.
A plain B12 shot gives you only vitamin B12. A lipotropic shot adds methionine, inositol and choline, which may suit people who want broader support during a diet. Neither one is a weight loss drug.
Fat-dissolving injections are different again. They're cosmetic treatments injected into a specific area, such as under the chin, to break down local fat. Lipotropic shots don't target any one spot. If your main goal is losing a significant amount of weight, prescription GLP-1 medications have much stronger evidence, and your clinician can discuss whether they suit you.
Lipotropic injections are generally well tolerated, but they're compounded products that are not FDA-approved, so a clinician screens you first and you should report any problems.
Independently licensed U.S. physicians supervise every treatment we offer.

Board-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.

Trained at Columbia and Washington University, he pairs prescriptions with practical habits around food, training and sleep.

An OB-GYN for more than 40 years and a Fellow of ACOG, she leads women's health care, from perimenopause to PCOS.
Still deciding? The first consultation is free and takes about 5–10 minutes.
Book a free consultationPricing starts at $69 a month and depends on the blend and how often you inject. Your first consultation is free, and insurance isn't needed. Your clinician confirms the exact cost before prescribing.
Not on their own. There's limited evidence they cause meaningful weight loss by themselves. They're best seen as a supplement to a diet, exercise or medication plan.
Methionine, inositol and choline. Most MIC shots also contain vitamin B12, which is why you'll often see them called MIC + B12 injections.
No. They're compounded by licensed U.S. pharmacies and are not FDA-approved. The FDA doesn't review compounded products for safety or effectiveness before they reach the market.
Usually once or twice a week. Most people start weekly, and your clinician may adjust the schedule after reviewing how you feel.
Many people use lipotropic shots alongside a GLP-1 medication. Your clinician will review all your medicines before prescribing, and compounded GLP-1 medications are also not FDA-approved.
A B12 shot contains only vitamin B12. Lipotropic shots add methionine, inositol and choline. If your main issue is low B12, a B12-only plan may be all you need.
Yes. You'll get instructions on drawing up the dose, choosing a site and disposing of needles. Message the care team if you're unsure about anything.
Some people report feeling more energetic within a few weeks, but results vary and aren't predictable. Weight changes depend mostly on the rest of your plan.
Yes. Eggs, meat, fish and dairy supply choline, methionine and B12, and fruits, beans and grains provide inositol. A clinician can help you decide whether injections add anything for you.
No. Fat-dissolving injections are cosmetic treatments placed into a specific area to reduce local fat. Lipotropic shots are nutrient injections and don't target any one spot.
Sometimes. Depending on your history, your clinician may ask for recent results or order labs before prescribing.
People who are pregnant or breastfeeding, allergic to cobalt or B12, or have significant liver or kidney disease should talk through alternatives. Your clinician will tell you if they aren't a good fit.
Plans start at $69 a month with home delivery from a licensed U.S. pharmacy. Book a free 5–10 minute phone or video visit to see if MIC + B12 fits your plan.
Medically reviewed October 2026. This page is general information and not a substitute for advice from your own clinician. Read our editorial policy.