Dr. Benjamin H. Krasne, M.D.
Board-certified physicianBoard-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.
ED and desire in one tablet
Tadalafil Triple Action Blend online for ED and desire
One dissolvable tablet that pairs tadalafil 10 mg with PT-141 and oxytocin, for men whose concern is desire and connection as well as erections. It is compounded, costs $99 and is only prescribed after a clinician review.
- Tadalafil, PT-141 and oxytocin
- Dissolvable tablet, no injection
- $99 after a clinician review
Free to book. You pay only if you go ahead with treatment.
$99per supply
Licensed U.S. clinician review
Contains: Tadalafil, PT-141 and oxytocin
$99transparent price
5–10 minphone or video
No insuranceneeded
LicensedU.S. clinicians
Why get the tadalafil Triple Action Blend from us
Three ingredients, one dose
Each tablet pairs tadalafil 10 mg for erections with PT-141 for desire and oxytocin, so you take one dissolvable tablet instead of several products.
Honest comparison
Your clinician tells you plainly whether the blend makes sense or whether plain FDA-approved tadalafil or sildenafil is the better choice.
Careful safety review
A licensed U.S. clinician checks your heart health, blood pressure and medicine list, including nitrates and naltrexone, before prescribing.
Discreet delivery
The compounded blend ships in plain packaging from a licensed U.S. compounding pharmacy. Compounded medicines are not FDA-approved.
How to get the Triple Action Blend online
- 1
Pick a time for your free visit
Book online and pick phone or video. The first consultation costs nothing and no insurance is needed.
- 2
Talk with a clinician
In about 5–10 minutes, a licensed clinician asks about erections, desire, blood pressure, heart history and every medicine you take.
- 3
Your prescription is sent
If the blend is appropriate, it is prescribed and sent to a licensed U.S. compounding pharmacy, with clear directions on timing and limits.
- 4
Check in and adjust
Let the care team know how it went, including any nausea, flushing or headache. Your clinician can switch you to a different option if needed.
Who the Triple Action Blend is for
ED plus low desire
Standard ED pills help mechanically, but low interest or arousal is still getting in the way of intimacy.
Low desire on certain medicines
Some men notice reduced desire with antidepressants or stress. PT-141 acts on a different brain pathway, which is why some clinicians consider it in this situation.
Prefer one tablet
Instead of juggling separate prescriptions, the blend combines the three ingredients in a single as-needed dose.
Not for nitrates, riociguat or heart disease
Anyone who takes nitrates or riociguat, has uncontrolled high blood pressure or has significant heart disease should not use the blend.
Not needed if tadalafil alone works
If your only issue is getting or keeping an erection, generic tadalafil or sildenafil alone is usually simpler and costs less.
Tadalafil Triple Action Blend vs. tadalafil alone
| Feature | Triple Action Blend | Generic tadalafil |
|---|---|---|
| Ingredients | Tadalafil 10 mg, PT-141, oxytocin | Tadalafil only |
| Helps with | Erections plus desire | Erections |
| Form | Dissolvable tablet | Swallowed tablet, as needed or daily |
| FDA status | Compounded, not FDA-approved | FDA-approved |
| Price | $99 | ED plans from $39/mo |
What is the tadalafil Triple Action Blend?
Most ED pills act only on blood flow. The Triple Action Blend combines three ingredients that act in different places: tadalafil 10 mg supports the physical side of an erection, PT-141 (bremelanotide) 2000 mcg acts in the brain on sexual desire and arousal, and oxytocin 100 IU is a hormone the body naturally releases during closeness and orgasm. Each tablet dissolves in the mouth, so there is nothing to inject.
The blend is made by a licensed U.S. compounding pharmacy. Compounded medicines are prepared for an individual patient on a prescription and are not FDA-approved, which means the FDA has not reviewed this combination for safety, effectiveness or quality. Tadalafil on its own is an FDA-approved medicine (the active ingredient in Cialis). Bremelanotide is FDA-approved only as an injection for low desire in premenopausal women, so its use here, and the use of oxytocin for intimacy, is off-label.
Because the tablet contains a full ED medicine plus two other active ingredients, it is not a casual add-on. Your clinician will check your heart health, blood pressure and medicine list, and will tell you plainly whether the blend makes sense for you or whether plain tadalafil or sildenafil is the better choice.
Tadalafil, PT-141 and oxytocin: what each ingredient does
The three ingredients work through separate mechanisms, which is the reasoning behind combining them. The evidence base differs for each one, and the combination itself has not been studied in large clinical trials.
- Tadalafil 10 mg: a PDE-5 inhibitor that helps blood flow into the penis when you are aroused. Its effect lasts much longer than sildenafil's, so timing is flexible.
- PT-141 (bremelanotide) 2000 mcg: activates melanocortin receptors in the brain linked to sexual desire. As an FDA-approved injection it is labeled only for premenopausal women with low desire. Use in men is off-label.
- Oxytocin 100 IU: a hormone released naturally during touch and orgasm. Research on added oxytocin for intimacy is early and mixed, and effects, if any, tend to be subtle.
How to take the Triple Action Blend
Let the tablet dissolve fully in your mouth rather than swallowing it whole. Your clinician will tell you how long before intimacy to take it. Because PT-141 typically needs time to act, many people take it somewhat ahead of time. Take no more than one dose in 24 hours, and do not combine it with any other ED medicine unless your clinician says so.
Nausea is more likely with the first doses because of the PT-141. Taking the dose when you can sit quietly for a while, and not on an empty stomach, may help. If nausea or flushing is hard to tolerate, tell your clinician rather than adjusting the dose yourself.
Triple Action Blend vs. tadalafil alone
Plain generic tadalafil is FDA-approved, has a long safety record and comes in an everyday low dose as well as an as-needed dose. For many men it is all they need. The blend is a reasonable conversation when desire or connection is a real part of the problem, and you accept that its added ingredients rest on thinner evidence and that the product is compounded rather than FDA-approved.
Triple Action Blend side effects and safety
The blend carries the warnings of each ingredient. Your clinician will only prescribe it after reviewing your heart health, blood pressure and full medicine list.
- Never take it with nitrates (nitroglycerin, isosorbide), 'poppers' or riociguat. Tadalafil combined with these can cause a dangerous fall in blood pressure.
- PT-141 can raise blood pressure and lower heart rate for several hours after a dose, so it is not for people with uncontrolled high blood pressure or heart disease.
- Common side effects include nausea, flushing, headache, stuffy nose and back or muscle aches.
- Repeated PT-141 use can darken skin on the face, gums or breasts, and this may not fade after stopping.
- Get emergency care for an erection lasting more than 4 hours, chest pain or fainting. Seek help at once for sudden loss of vision or hearing.
- Tell your clinician if you take oral naltrexone, alpha-blockers or other blood pressure medicines, as doses may need to change.
Physicians who oversee your care
Independently licensed U.S. physicians supervise every treatment we offer.
Dr. Johnathan Chance Miller, M.D.
PhysicianTrained at Columbia and Washington University, he pairs prescriptions with practical habits around food, training and sleep.
Dr. Vanessa Niles, R.N., M.D., F.A.C.O.G.
OB-GYN, board certifiedAn OB-GYN for more than 40 years and a Fellow of ACOG, she leads women's health care, from perimenopause to PCOS.
Triple Action Blend FAQs
Still deciding? The first consultation is free and takes about 5–10 minutes.
Book a free consultationWhat is in the Triple Action Blend?
Each dissolvable tablet contains tadalafil 10 mg, PT-141 (bremelanotide) 2000 mcg and oxytocin 100 IU. It is prepared by a licensed U.S. compounding pharmacy on a prescription.
Is the Triple Action Blend FDA-approved?
No. It is a compounded medicine, and compounded products are not FDA-approved. Tadalafil alone is FDA-approved, but this specific combination has not been reviewed by the FDA.
How much does the Triple Action Blend cost?
The Triple Action Blend is $99. Your first consultation is free and you do not need insurance.
How is the Triple Action Blend different from Cialis?
Cialis contains only tadalafil, which helps with the physical side of erections. The blend adds PT-141, which acts on desire in the brain, and oxytocin, which is linked to closeness. Cialis is a brand name owned by its manufacturer.
How long before sex should I take the blend?
Your clinician will give you a timing window. Tadalafil acts over a long period, while PT-141 usually takes some time to start working, so the dose is often taken well before intimacy rather than at the last minute.
How often can I take the blend?
No more than once in 24 hours, and only as often as your clinician directs. Frequent PT-141 use raises the chance of skin darkening, so most plans keep doses occasional.
Can I take the blend with daily tadalafil?
Not unless your clinician specifically approves it. Doubling up on tadalafil raises the risk of low blood pressure and side effects.
Why does the blend cause nausea?
Nausea is the most common side effect of PT-141, especially with the first few doses. It often eases over time. Tell your clinician if it does not.
Is tadalafil safe with blood pressure medicine?
It depends on the medicine and how well your blood pressure is controlled. Your clinician will review this carefully, because tadalafil can lower blood pressure while PT-141 can raise it briefly.
Can women use the blend?
This blend is prescribed for men with erectile concerns because of its tadalafil content. Women interested in desire treatment can ask about PT-141 troches or other options.
What if the Triple Action Blend doesn't work?
Your clinician may suggest plain tadalafil or sildenafil, a different dose or a check for causes such as low testosterone. Not every treatment works for every person.
Can I get the blend without a consultation?
No. It requires a prescription from a licensed clinician who has reviewed your health. That review is what keeps the combination as safe as possible.
Is the Triple Action Blend shipped discreetly?
The compounding pharmacy ships it in plain packaging. Delivery times can vary by pharmacy and location.
Get the tadalafil Triple Action Blend online
Book a free 5–10 minute phone or video visit. If the blend suits you, a licensed clinician prescribes it for $99, delivered in plain packaging.
Related treatments
References
- MedlinePlus: Tadalafil drug information
- MedlinePlus: Bremelanotide injection
- FDA: Compounding and the FDA, questions and answers
- MacDonald et al. Review of safety and side effects of intranasal oxytocin (PubMed)
Medically reviewed October 2026. This page is general information and not a substitute for advice from your own clinician. Read our editorial policy.
$99per supply
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