
Dr. Benjamin H. Krasne, M.D.
Board-certified physicianBoard-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.
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Compounded NAD+ shipped to you
NAD+ is a molecule every cell uses to make energy. If a licensed clinician thinks it is reasonable for you, compounded NAD+ is shipped with supplies and instructions for small injections under the skin.
Free to book. You pay only if you go ahead with treatment.
Instead of sitting through a long clinic drip, you give yourself small injections under the skin at home, with syringes and written instructions included.
Your clinician usually starts you on a low dose and adjusts it with you, typically about 50–100 mg one to three times a week.
We're clear that compounded NAD+ is not FDA-approved and that long-term evidence in people is limited, so you can decide with realistic expectations.
If fatigue is your concern, a licensed clinician helps rule out other causes before NAD+, and reviews your history and medications for safety.
Choose phone or video. In about 5–10 minutes, a licensed clinician reviews your goals, health history and medications.
If you mainly want help with low energy, your clinician may suggest labs to check for common treatable causes before starting NAD+.
If your clinician decides NAD+ is appropriate, a licensed U.S. compounding pharmacy prepares it and ships vials, syringes and instructions to you.
Your care team explains how to draw up a dose, where to inject and how to dispose of sharps safely. You can ask questions before your first dose.
Your clinician reviews side effects and whether you notice any benefit, then adjusts the dose or schedule or stops treatment.
Most people asking about NAD+ already pay attention to sleep, exercise and standard lab markers and want to try an additional option.
Injections go just under the skin of the belly or thigh with a short, fine needle. You will be shown how and given written steps.
You should be at ease paying for a treatment whose benefits in people are not established, and stopping if you notice nothing.
NAD+ is not prescribed during active cancer treatment without your oncologist's agreement, or during pregnancy or breastfeeding, as safety has not been studied.
Ongoing tiredness can come from anemia, thyroid problems, sleep apnea, depression and more. Your clinician may suggest testing for these first.
| Option | How it's taken | Dose per use | Where |
|---|---|---|---|
| NAD+ injection | Under the skin, one to three times weekly | About 50–100 mg | At home |
| IV NAD+ infusion | Into a vein over several hours | Larger amounts | In a clinic |
| NAD+ nasal spray | Needle-free spray | Smaller dose per use | At home |
| Oral precursors (like nicotinamide riboside) | Supplement by mouth | Varies by product | At home |
Nicotinamide adenine dinucleotide, or NAD+, is a coenzyme found in every living cell. It helps turn food into usable energy and is needed by enzymes involved in DNA repair and cell maintenance, including the sirtuin family that is often discussed in aging research.
Studies in animals and people suggest NAD+ levels tend to fall with age in some tissues. That has led researchers to test ways of raising it, mostly with oral precursors such as nicotinamide riboside and nicotinamide mononucleotide. A 2020 review of the research found promising results in animal studies but concluded that long-term human trials are still early, and direct NAD+ showed weaker effects than its precursors in the studies reviewed.
The NAD+ injections we prescribe are made by licensed U.S. compounding pharmacies. Compounded drugs are not FDA-approved, which means the FDA has not checked their safety, effectiveness or quality before sale. NAD+ is not approved to treat or prevent any condition, and any benefit for energy or aging is not proven.

NAD+ injections are given subcutaneously, into the fat just under the skin. Your clinician usually starts with a low dose to see how you react. A common range is about 50–100 mg per injection, given one to three times a week. Some people use NAD+ in cycles, with breaks between them.
Inject slowly. A quick injection is more likely to sting or cause flushing. Rotate sites between the belly and thighs, and keep vials stored as the pharmacy label directs.
Oral precursors such as nicotinamide riboside are sold as supplements and have been studied more than injected NAD+. IV NAD+ infusions deliver larger amounts over several hours in a clinic. NAD+ nasal spray is a needle-free option with a smaller dose per use.
No route has strong evidence that it slows aging in people. The choice usually comes down to convenience, cost and how you tolerate it. Your clinician can talk through which, if any, makes sense for you.
NAD+ injections are generally reported to be well tolerated, but long-term safety data in people are limited. A 2020 review noted possible theoretical concerns with boosting NAD+, including effects on tumor growth and cell aging, that still need study.
Independently licensed U.S. physicians supervise every treatment we offer.

Board-certified in anesthesiology, he reads medications and metabolism with a pharmacologist's eye, which shapes how he doses weight loss and longevity care.

Trained at Columbia and Washington University, he pairs prescriptions with practical habits around food, training and sleep.

An OB-GYN for more than 40 years and a Fellow of ACOG, she leads women's health care, from perimenopause to PCOS.
Still deciding? The first consultation is free and takes about 5–10 minutes.
Book a free consultationNo. NAD+ injections are compounded by licensed U.S. pharmacies and are not FDA-approved for any use. The FDA does not review compounded drugs for safety, effectiveness or quality before they are sold.
NAD+ injections are $165 per month. Your first consultation is free, and you do not need insurance. Your clinician confirms costs before prescribing.
It helps cells convert food into energy and supports enzymes involved in DNA repair and cell maintenance. Whether adding NAD+ from outside the body improves health or aging in people is still being studied.
Not in people. Most research has used oral precursors, and reviews describe human trials as early. Animal studies are more encouraging but do not prove a human benefit.
Commonly one to three times a week, at about 50–100 mg per injection, though your clinician may start lower. Some people take planned breaks.
The needle is short and fine, and most people feel a brief pinch. Injecting slowly reduces stinging and flushing.
Yes. Your care team explains how to prepare a dose, where to inject and how to dispose of sharps, and you can ask questions before your first injection.
IV infusions deliver a larger amount over hours in a clinic. Injections are smaller doses you give yourself at home. Neither has proven anti-aging benefits.
They are an option, and they have more human study data than injected NAD+. Supplements are not reviewed by the FDA for effectiveness, so ask your clinician about quality and fit.
Some people report changes in energy within a few weeks, and others notice nothing. If you see no benefit after a fair trial, your clinician may suggest stopping.
Often, yes. NAD+ has few known drug interactions, but your clinician still reviews your full medication list before adding it.
Not always. If you want NAD+ mainly for tiredness, your clinician may order labs to look for common causes such as anemia or thyroid problems first. Those tests can be done at a draw site near you, and any cost is confirmed in advance.
People in active cancer treatment without their oncologist's input, and anyone pregnant or breastfeeding. Your clinician also screens for other conditions during the visit.
Book a free 5–10 minute phone or video visit. If a licensed clinician decides NAD+ is reasonable for you, it's $165/mo with compounded NAD+ and supplies shipped to you.
Medically reviewed October 2026. This page is general information and not a substitute for advice from your own clinician. Read our editorial policy.